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Prurigo Nodularis

What is it? Prurigo Nodularis (PN) is a chronic inflammatory skin disease characterized by intensely itchy, firm bumps (nodules) that develop as a result of persistent scratching and an ongoing itch- scratch cycle. The condition commonly affects the arms, legs, and trunk and can cause severe itch, sleep disturbance, skin pain, and significant impacts on quality of life, emotional well-being, and daily functioning. PN is often difficult to manage and may persist despite treatment with conventional therapies.

Current available trials:

  • Adults (≥18 years) newly initiating Nemluvio® (nemolizumab) for Prurigo Nodularis.

  • Physician-confirmed moderate-to-severe PN treated according to routine clinical practice.

  • Must provide written informedconsent.

  • No prior treatment with nemolizumab.

  • Participation includes approximately 12 months of follow-up and completion of study questionnaires.

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